Welcome to the Personal Website of Zicheng Wang

About Me

I am Zicheng Wang (汪子承), a Ph.D. candidate in the Program of Human Genetics (Computational Track) at the University of Chicago (UChicago), advised by Prof. Xin He. My research lies at the intersection of AI/ML, functional genomics, and human genetics. I develop computational and deep learning methods—including sequence-to-function modeling and multimodal deep learning—to understand gene regulation and the genetic basis of complex traits. My work also integrates single-cell multiomic data with genome-wide association studies (GWAS).

Education and Research Experience

I am currently a Research Intern at Genentech (June–September 2026), working on AI for Biology under the mentorship of Bryce van de Geijn.

Before joining UChicago, I earned a Master’s degree in Computational Biology from the Harvard T.H. Chan School of Public Health. My master’s thesis, supervised by Prof. Liming Liang, explored the shared genetics between Alzheimer’s disease and strokes using GWAS data. I also worked with Dr. Mercedeh Movassagh in the Rafael Irizarry Lab at the Dana-Farber Cancer Institute, investigating the genomic regulation of non-coding RNAs in hydrocephalus.

I hold Bachelor’s degrees in Biological Sciences and Quantitative Economics from the University of California, Irvine, with a minor in Statistics. During my undergraduate studies, I conducted neuropharmacology research under Prof. Olivier Civelli and Prof. Amal Alachkar.

Selected Publication

Lifan Liang^†, Siwei Zhang^†, Zicheng Wang^†, Hanwen Zhang^†, Chuxuan Li^†, Christina Thapa, Emily K. Oh, David Sirkin, Xiaotong Sun, Alexandra Barishman, Ada McCarroll, Alexandra C. Duhe, Sheng Qian, Xiaoyuan Zhong, Brendan Jamison, Whitney Wood, Alena Kozlova, Zhiping P. Pang, Alan R. Sanders, Xin He, and Jubao Duan. Single-cell multiomics of neuron activation reveals context-specific genetics of brain disorders. Science 392, eadw3949 (2026).

^† These authors contributed equally as co-first authors.

For a complete and up-to-date publication list, please visit my Google Scholar profile.

Feel free to explore this site to learn more about my work, publications, and ongoing projects.